Health Care Excipients - Solubilizers for High-Risk Applications

VitiPure CO 35 is a non-ionic solubiliser and emulsifying agent for the human and veterinary pharmaceutical industries. It is made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. At room temperature it appears as pale-yellow oily liquid. It forms clear solutions in water. The LEX grade represents Low Endotoxins & Low bioburden grade product especially suitable for customers using it in high-risk applications.

VitiPure CO 35 Superior is a non-ionic solubilizer and emulsifying agent for human and veterinary pharmaceutical markets. It is manufactured by ethoxylating castor oil in a molar ratio of 1:35. VitiPure CO 35 Superior is then purified with a patented process to reduce residual impurities yielding transparent almost colorless oily liquid which forms clear solutions in water. Typically used in sensitive applications where final formulations need to be colorless, or the API is sensitive to residual impurities. And where the end formulation needs to have low microbial load with low endotoxins.

VitiPure HCO 40 is versatile non-ionic solubilizer and emulsifier enhancing the solubility and bioavailability of hydrophobic APIs and fat-soluble vitamins. VitiPure HCO 40 is obtained by reacting 40 moles of ethylene oxide with 1 mole of hydrogenated castor oil. At the room temperature it appears as white to yellowish paste. VitiPure HCO 40 is suitable for SEDDS and SMEDDS. The LEX grade represents Low Endotoxins & Low bioburden grade product especially suitable for customers using it in high-risk applications.

VitiPure L 20 is a non-ionic, hydrophilic emulsifier, co-emulsifier and solubilizer. It is an oily, yellow or brownish-yellow, clear or slightly opalescent liquid with a faint odor. VitiPure L 20 can be used in various pharmaceutical formulations. The LEX grade represents Low Endotoxins & Low bioburden grade product especially suitable for customers using it in high-risk applications.Generic name: Polysorbate 20

VitiPure LEX 300 is a low molecular weight polyethylene glycol excipient type of the VitiPure LEX range for sensitive APIs and formulations. With defined microbiological and endotoxin checks of the final packed product batch, which are given individually on the certificate of analysis, we would like to support you in your individual formulation risk assessment.

VitiPure LEX 400 is a low molecular weight polyethylene glycol excipient type of the VitiPure LEX range for sensitive APIs and formulations. With defined microbiological and endotoxin checks of the final packed product batch, which are given individually on the certificate of analysis, we would like to support you in your individual formulation risk assessment.

VitiPure Meglumine LEX improves the solubility and bioavailability of APIs. Meglumine is a multi-talented functional excipient which is used as a counter-ion to form a salt with the API, or as a standard excipient to modify the pH to enhance the API solubility and stability. Traditionally, Meglumine is used as a counter-ion in contrast media. Applications include oral solid, and liquid formulations. And, widely used in sensitive formulations where low bioburden and low endotoxin grade is required.

VitiPure O 80 is a non-ionic, hydrophilic emulsifier, co-emulsifier, solubilizer and suspension stabilizer used widely in various biopharmaceutical formulations. It appears as amber liquid in room temperature with a faint characteristic odor. VitiPure O 80 has a broad working pH range and offers good skin tolerance. The LEX grade represents Low Endotoxins & Low bioburden grade product especially suitable for customers using it in high-risk applications. Generic name: Polysorbate 80

VitiPure O 80 Superior is a non-ionic solubilizer and emulsifying agent for human and veterinary pharmaceutical markets. It is manufactured by ethoxylating sorbitan mono-oleate in a molar ratio of 1:20. VitiPure O 80 Superior is then purified with a patented process to reduce residual impurities yielding a transparent almost colorless oily liquid. Typically used in sensitive formulations where final formulations need to be colorless, or the API is sensitive to residual impurities. And, where the end formulation needs to have low microbial load with low endotoxins.