Skip to main content

Health Care Active Pharmaceutical Ingredients

Polyethylene Glycols bring constipation relief

PEG APIs to bring constipation relief in Laxative formulations

Gentle on the body, for better quality of life

Key benefits of PEG laxatives:
  • Absence of side effects compared with other types of osmotic laxatives such as lactulose
  • Gentle on the body - because the PEG is almost completely excreted, with very low levels of absorption by the digestive tract
  • Suitable for long-term use by children as young as two years old for special PEG laxatives
Clariant Image Baking Soda 20221101

This type of laxative thus improves quality of life for millions around the world, as part of treatment for chronic constipation in adults and children, during pregnancy, or before surgery or colonoscopy continue to improve people’s health, we have several excipients in our portfolio that are used across multiple applications allowing pharmaceutical formulators to enhance the bioavailability of poorly soluble APIs.

Our laxative API PEGs are compliant with the general requirements of three of the most important international pharmacopoeias (the European Pharmacopoeia (Ph. Eur.), the United States Pharmacopoeia–National Formulary (USP-NF), and the Japanese Pharmacopoeia (JP)). With more than 25 years ’ experience as a producer, we maintain very rigorous production standards. We use dedicated re actors to avoid cross contamination and our production facilities undergo comprehensive audits for GMP compliance.

PEG API as a humectant for an immediate relief in ophthalmic formulations

Many people around the world have eye issues. In many cases these problems are minor and are easy to treat at home, while of course others need the attention of a specialist. The minor cases can be treated by using eye drops and lubricants that are effective and less painful. These are used for the treatment of eye diseases and disorders such as dry eye, redness or itching, among others proving to the patient an immediate, lasting relief.

Polyglykol 400 J is a liquid PEG API grade product, produced under ICH Q7 conditions and GMP certified by the German authorities. It is specified according to the requirements of the international ICH guidelines and monographs. With its additional microbiological specification (incl. endotoxins) special formulation requirements could be fulfilled.

Clariant Image Eyedrop in blue transparent container 20220823

Excellence in production

Clariant is committed on Excellence in production with a global production, technical and regulatory footprint. Clariant also offers PEGs as APIs in various physical forms
  • Flakes
  • Sprayed powders
  • Milled powders

Resources

Related products

  • Polyglykol 3350 P*

    Polyglykol 3350 P is a milled PEG API grade powder product, produced under ICH Q7 conditions with GMP certification by the German authorities.The powder form supports the homogeneous mixing with other materials within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 3350 PS

    Polyglykol 3350 PS is a sprayed PEG API grade powder product, with a mean particle size distribution. It is produced under ICH Q7 conditions and GMP certified by the German authorities. The powder form supports the homogeneous mixing with other powder materials within production resulting into powder mixtures with improved flowability. It is specified according to the requirements of the main international ICH guidelines and monographs (see below).

    more
  • Polyglykol 3350 PSB

    Polyglykol 3350 PS is a sprayed PEG API grade powder product, with a coarse particle size distribution. It is produced under ICH Q7 conditions and GMP certified by the German authorities. The powder form supports the homogeneous mixing with other powder materials within production resulting into powder mixtures with improved flowability. It is specified according to the requirements of the main international ICH guidelines and monographs (see below).

    more
  • Polyglykol 3350 PSE

    Polyglykol 3350 PSE is a sprayed PEG API grade powder product, with a mean particle size distribution. It is produced under ICH Q7 conditions and GMP certified by the German authorities. The powder form supports the homogeneous mixing with other powder materials within production resulting into powder mixtures with improved flowability. It is specified according to the requirements of the main international ICH guidelines and monographs (see below).With its low Ethylene oxide and Dioxane specification limits special formulation requirements could be fulfilled.

    more
  • Polyglykol 3350 PSR

    Polyglykol 3350 PSR is a sprayed PEG API grade powder product, with a coarse particle size distribution. It is produced under ICH Q7 conditions and GMP certified by the German authorities. The powder form supports the homogeneous mixing with other powder materials within production resulting into powder mixtures with improved flowability. It is specified according to the requirements of the main international ICH guidelines and monographs (see below).With its low Ethylene oxide and Dioxane specification limits special formulation requirements could be fulfilled.

    more
  • Polyglykol 3350 PST

    Polyglykol 3350 PST is a sprayed PEG API grade powder product, with a fine particle size distribution. It is produced under ICH Q7 conditions and GMP certified by the German authorities. The powder form supports the homogeneous mixing with other powder materials within production resulting into powder mixtures with improved flowability. It is specified according to the requirements of the main international ICH guidelines and monographs (see below).With its low Ethylene oxide and Dioxane specification limits special formulation requirements could be fulfilled.

    more
  • Polyglykol 3350 S*

    Polyglykol 3350 S is a flaked PEG API grade powder product, produced under ICH Q7 conditions with GMP certification by the German authorities.The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 400 J

    Polyglykol 400 J is a liquid PEG API grade product, produced under ICH Q7 conditions and GMP certified by the German authorities. It is specified according to the requirements of the international ICH guidelines and monographs. With its additional microbiological specification (incl. endotoxins) special formulation requirements could be fulfilled.

    more
  • Polyglykol 4000 P*

    Polyglykol 4000 P is a milled PEG API grade powder product, produced under ICH Q7 conditions with GMP certification by the German authorities.The powder form supports the homogeneous mixing with other materials within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 4000 PS

    Polyglykol 4000 PS is a sprayed PEG API grade powder product, with a mean particle size distribution. It is produced under ICH Q7 conditions and GMP certified by the German authorities. The powder supports the homogeneous mixing with other powder materials within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below).

    more
  • Polyglykol 4000 S*

    Polyglykol 4000 S is a flaked PEG API grade powder product, produced under ICH Q7 conditions with GMP certification by the German authorities.The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more

Get In contact