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Health Care Excipients

Excipients to enhance medicines

Excipients for effective solubilization and bioavailability enhancement of APIs

 

At your service, with a broad portfolio

With a positive and progressive track-record in the pharmaceutical industry, Clariant has a wide product portfolio of Excipients beneath the brands VitiPure®, Polyglykols®, Lanogen® and Motusflex®

About 40% of patent-protected pharmaceutical compounds are poorly water soluble and a significant percentage cannot be absorbed effectively due to their complex chemical structures or absorption profiles.

How can Clariant help you to get a solution? We offer a wide range of solubilizers that will increase the API performance
  • Solvents
  • PEG-Derivatives
  • Poloxamer

Moreover, our Excipients are supporting drug formulations as Emulsifiers, Rheology Modifiers, Binders, Humectants, Plasticizers etc. for all sorts of pharmaceutical dosage applications.

Our specialties are globally known for their high quality. Our principle is to provide superior performance products to deliver effective solutions to our customers.

With a robust Global Product Stewardship service in place, Clariant’s approach to health, safety and environmental protection is governed by the principles of sustainable development and by our participation in Responsible Care Initiative.

We provide all the documents for qualification, registration and risk assessment as per current EMA / FDA regulatory guidelines.

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Related Products

  • Lanogen® 1500

    Lanogen® 1500 is a mixture of Polyglykol 300 and 1500 in a 50 :50 ratio, which is produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). This ready-made mixture eases the production of ointments.

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  • Motusflex HV

    Motusflex HV is a high viscosity rheology modifier & synthetic polymer used as a gelling agent for aqueous systems and as a texturizer and thickener for oil-in-water emulsions. Motusflex HV provides formulations with excellent yield value, corresponding to superior stability even in the absence of additional emulsifier. This product has a good compatibility with APIs and organic solvents (ethanol, acetone) and is stable towards UV radiation and high shear stress.

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  • Motusflex LV

    Motusflex LV is a low viscosity rheology modifier & synthetic polymer. Motusflex LV consists of a large, hydrophilic portion and a smaller hydrophobic portion. This chemical structure allows this copolymer to function as primary emulsifier and stabilizer in oil-in-water emulsions. This is done as the hydrophobic portion adsorbs at the oil-water interface, and the hydrophilic portion swells in the water phase to provide exceptional emulsion stability to a broad range of oils. In combination with other polymers like Motusflex HV, Motusflex LV can be used to modify skin rheology and texture, improve pick up as well as to reduce the total amount of required thickener. It is indicated for low-viscosity formulations like lotions, wet wipes, sprayable formulations, hot and cold O/W formulations with an elegant and rich skin after-feel.

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  • Motusflex MF

    Motusflex MF is a multi-functional rheology modifier & synthetic polymer which offers the solution for complex skin formulations – a true partner which suits your specific requirements. Motusflex® MF is ready to use and easy to add at any formulation stage as it disperses quickly in the water or oil phase. It is easy to add Motusflex MF at any formulation step (oil or water phase) and cold processable.

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  • Polyglykol 1000*

    Polyglykol 1000 is a pasty PEG excipient grade product, produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

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  • Polyglykol 10000 S*

    Polyglykol 10000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

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  • Polyglykol 12000 S*

    Polyglykol 12000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 1500 fl*

    Polyglykol 1500 fl is a pasty PEG excipient grade product, produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 1500 S*

    Polyglykol 1500 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 200 USP

    Polyglykol 200 USP is a liquid PEG excipient grade product, produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below).

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  • Polyglykol 2000 S*

    Polyglykol 2000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 20000 P*

    Polyglykol 20000 P is a milled PEG excipient grade powder product, produced under IPEC GMP conditions. The powder form supports the homogeneous mixing with other materials within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 20000 S*

    Polyglykol 20000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 300*

    Polyglykol 300 is a liquid PEG excipient grade product, produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 3000 P*

    Polyglykol 3000 P is a milled PEG excipient grade powder product, produced under IPEC GMP conditions. The powder form supports the homogeneous mixing with other materials within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 3000 S*

    Polyglykol 3000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 35000 S*

    Polyglykol 35000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 400*

    Polyglykol 400 is a liquid PEG excipient grade product, produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 4000 PF*

    Polyglykol 4000 PF is a milled PEG excipient grade powder product with a fine particle size distribution, produced under IPEC GMP conditions. The powder form supports the homogeneous mixing with other materials within production. The fine particle size distribution supports granulation and compressing processes. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 600*

    Polyglykol 600 is a liquid PEG excipient grade product, produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 6000 P*

    Polyglykol 6000 P is a milled PEG excipient grade powder product, produced under IPEC GMP conditions. The powder form supports the homogeneous mixing with other materials within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 6000 PF*

    Polyglykol 6000 PF is a milled PEG excipient grade powder product with a fine particle size distribution, produced under IPEC GMP conditions.The powder form supports the homogeneous mixing with other materials within production. The fine particle size distribution supports granulation and compressing processes. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 6000 S*

    Polyglykol 6000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 8000 P*

    Polyglykol 8000 P is a milled PEG excipient grade powder product, produced under IPEC GMP conditions. The powder supports the homogeneous mixing with other materials within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 8000 PF*

    Polyglykol 8000 PF is a milled PEG excipient grade powder product with a fine particle size distribution, produced under IPEC GMP conditions.The powder form supports the homogeneous mixing with other materials within production.The fine particle size distribution supports granulation and compressing processes. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • Polyglykol 8000 S*

    Polyglykol 8000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA

    more
  • VitiPure CO 35

    VitiPure CO 35 is a non-ionic solubiliser and emulsifying agent for the human and veterinary pharmaceutical industries. It is made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. At room temperature it appears as pale-yellow oily liquid. It forms clear solutions in water. It is typically used into formulations such as Topicals (Cream, Hot processing), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Soft shell capsules, Tablets, Instant release), Liquid preparations (Solution).

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  • VitiPure CO 35 LEX

    VitiPure CO 35 is a non-ionic solubiliser and emulsifying agent for the human and veterinary pharmaceutical industries. It is made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. At room temperature it appears as pale-yellow oily liquid. It forms clear solutions in water. The LEX grade represents Low Endotoxins & Low bioburden grade product especially suitable for customers using it in high-risk applications.

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  • VitiPure HCO 40

    VitiPure HCO 40 is versatile non-ionic solubilizer and emulsifier enhancing the solubility and bioavailability of hydrophobic APIs and fat-soluble vitamins. VitiPure HCO 40 is obtained by reacting 40 moles of ethylene oxide with 1 mole of hydrogenated castor oil. At the room temperature it appears as white to yellowish paste. VitiPure HCO 40 is suitable for SEDDS and SMEDDS. It is typically used into formulations such as Topicals (Cream, Hot processing), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Soft shell capsules, Tablets, Instant & modified release), Liquid preparations (Solution).

    more
  • VitiPure HCO 40 LEX

    VitiPure HCO 40 is versatile non-ionic solubilizer and emulsifier enhancing the solubility and bioavailability of hydrophobic APIs and fat-soluble vitamins. VitiPure HCO 40 is obtained by reacting 40 moles of ethylene oxide with 1 mole of hydrogenated castor oil. At the room temperature it appears as white to yellowish paste. VitiPure HCO 40 is suitable for SEDDS and SMEDDS. The LEX grade represents Low Endotoxins & Low bioburden grade product especially suitable for customers using it in high-risk applications.

    more
  • VitiPure L 20

    VitiPure L 20 is a non-ionic, hydrophilic emulsifier, co-emulsifier and solubilizer. It is an oily, yellow or brownish-yellow, clear or slightly opalescent liquid with a faint odor. VitiPure L 20 can be used in various pharmaceutical formulations. It is typically used into formulations such as Topicals (Cold processing, Hot processing, Cream, Emulsion, Foam, Gel), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Soft shell capsules, Tablets, Instant release), Liquid preparations (Solution, Suspension) and Suppositories.

    more
  • VitiPure L 20 LEX

    VitiPure L 20 is a non-ionic, hydrophilic emulsifier, co-emulsifier and solubilizer. It is an oily, yellow or brownish-yellow, clear or slightly opalescent liquid with a faint odor. VitiPure L 20 can be used in various pharmaceutical formulations. The LEX grade represents Low Endotoxins & Low bioburden grade product especially suitable for customers using it in high-risk applications.

    more
  • VitiPure LEX 300

    VitiPure LEX 300 are low molecular weight polyethylene glycols with stringent control of microbial load & low in endotoxins for pharmaceutical high-risk formulations. They are colorless and tasteless liquid at room temperature. They are readily soluble in common solvents such as water, ethanol, acetone, glycols etc.

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  • VitiPure LEX 400

    VitiPure LEX 400 are low molecular weight polyethylene glycols with stringent control of microbial load & low in endotoxins for pharmaceutical high-risk formulations. They are colorless and tasteless liquid at room temperature. They are readily soluble in common solvents such as water, ethanol, acetone, glycols etc.

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  • VitiPure O 80

    VitiPure O 80 is a non-ionic, hydrophilic emulsifier, co-emulsifier, solubilizer and suspension stabilizer used widely in various biopharmaceutical formulations. It appears as amber liquid in room temperature with a faint characteristic odor. VitiPure O 80 has a broad working pH range and offers good skin tolerance. It is typically used into formulations such as Topicals (Cold processing, Hot processing, Cream, Emulsion, Foam, Gel, Hydrophilic ointment, Lipophilic ointment), Solid orals (Hot melt extrusion, Spray drying, Conventional pellets, Hard shell capsules, Multiple-unit tablets, Single-unit tablets, Soft shell capsules, Tablets, Enteric release, Instant release, Aqueous Coating), Liquid preparations (Solution, Suspension) and Suppositories.

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  • VitiPure O 80 LEX

    VitiPure O 80 is a non-ionic, hydrophilic emulsifier, co-emulsifier, solubilizer and suspension stabilizer used widely in various biopharmaceutical formulations. It appears as amber liquid in room temperature with a faint characteristic odor. VitiPure O 80 has a broad working pH range and offers good skin tolerance. The LEX grade represents Low Endotoxins & Low bioburden grade product especially suitable for customers using it in high-risk applications.

    more
  • VitiPure P 188

    VitiPure P 188 is all rounder non-ionic polymer suitable for various pharmaceutical applications. It is supplied as a white to slightly yellowish flakes/powder with a waxy consistency. It is freely soluble in ethanol and water (opalescent solution). It is used as a wetting agent, emulsifier, solubilizer and bioavailability enhancer of poorly soluble APIs. It is typically used into formulations such as Topicals (Cream, Hot processing, Cold processing, Foam, Gel), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Instant release, extended release, matrix-type system, Reservoir-type system, Film), Liquid preparations (Solution).

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