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VitiPure P 188

Methyl Oxirane polymer with Oxirane

Edition Date :
July 07, 2022

VitiPure P 188 is all rounder non-ionic polymer suitable for various pharmaceutical applications. It is supplied as a white to slightly yellowish flakes/powder with a waxy consistency. It is freely soluble in ethanol and water (opalescent solution). It is used as a wetting agent, emulsifier, solubilizer and bioavailability enhancer of poorly soluble APIs. It is typically used into formulations such as Topicals (Cream, Hot processing, Cold processing, Foam, Gel), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Instant release, extended release, matrix-type system, Reservoir-type system, Film), Liquid preparations (Solution).

Benefits

  • It used as wetting agents, as emulsifiers and solubilizers
  • It improves the solubility, absorption and bioavailability of low-solubility actives
  • Suitable in solid dispersions and improves the solubility, absorption and bioavailability of low-solubility APIs in solid oral dosage forms.
  • Versatile solubilizer suitable to use in solid, semi-solid and liquid formulations
Chemical Name
  • Methyl Oxirane polymer with Oxirane
Product Function
  • Solublizers
  • Plasticizers
  • Emulsifier

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Applications

VitiPure P 188 is a non-ionic, hydrophilic emulsifier and/or solubilizer for pharmaceutical preparations. Applied in formulations   such as Skin Delivery, Softgels, Solubilization.

Generic Name

Poloxamer 188 (Ph. Eur., USP/NF)

Grade

IPEC GMP Pharma Grade 

Country of Origin

Spain

Manufacturer address

Clariant Ibérica Producción S.A., Autovía Tarragona-Salou, Km. 3,8, 43110 La Canonja Tarragona, Spain

Packaging size (Article Nr.)

100kg steel drum (Article Nr. 32217113215, 32217113216) and 25kg steel drum (Article Nr. 32217129285); Sample size 0.5kg

Retest period

24 months