Discover Value.
Discover Synergen™ ME.

Food for Tomorrow
and Beyond?


Nature gives us a lot 

Our daily challenge is to use it sustainably

About 10% of the Earth’s surface is suitable for efficient agricultural use. This limited area has to feed the world’s population—which is constantly growing by about 80 million people each year. That is only possible if harvests increase consistently. How can we achieve this? We visited a farmer and spoke to him about the challenges he faces every day in his fields.
Población mundial
Explosión de la población frente a
uso de la tierra ligeramente en aumento
Uso de la tierra para agricultura (mundial)

Effective Protection

means knowing the threats

  • Crop loss


    Smartweed loves wheat. Same goes for cutworms. Without agrochemicals and tank-mix adjuvants we could lose up to 50% of yields to them.

    100 %
    50 %
    Source: Oerke, E. C. »Crop losses to pests.«
    Journal of Agricultural Science 144 (2006): 31–43.

    Without the use of herbicides, massive crop loss would result due to pests, diseases and weeds. Current crop protection can reduce potential wheat crop loss by about:

    • Polygonum spp
    • Septoria Tritici
    • Euxoa auxiliaris
  • Crop loss


    Insects, weeds and diseases in rice fields can cause damage that leads to crop loss of up to 77%.

    100 %
    50 %
    Source: Oerke, E. C. »Crop losses to pests.«
    Journal of Agricultural Science 144 (2006): 31–43.

    Without the use of herbicides, massive crop loss would result due to pests, diseases and weeds. Current crop protection can reduce potential rice crop loss by about:

    • Echinochloa spp
    • Pyricularia Grisea
    • Spodoptera SPP
  • Crop loss


    Diseases like Potato Late Blight can be minimized dramatically by using an efficient working agrochemical combined with adjuvants.

    100 %
    50 %
    Source: Oerke, E. C. »Crop losses to pests.«
    Journal of Agricultural Science 144 (2006): 31–43.

    Without the use of herbicides, massive crop loss would result due to pests, diseases and weeds. Current crop protection can reduce potential potato crop loss by about:

    • Conoderus falli
    • Phytophthora infestans
    • Empoasca fabae Harris
  • Crop loss


    Asian Rust is threatening one of the world’s most important crops. We think soy is delicious. So we protect it.

    100 %
    50 %
    Source: Oerke, E. C. »Crop losses to pests.«
    Journal of Agricultural Science 144 (2006): 31–43.

    Without the use of herbicides, massive crop loss would result due to pests, diseases and weeds. Current crop protection can reduce potential crop loss of soy by about:

    • Conyza SPP
    • Phakopsora spp
    • Helicoverpa SPP
  • Crop loss


    Wind, rain, sunlight, pests—crops are exposed to numerous conditions in the field. Tank-mix adjuvants help agrochemicals to work more effectively in reducing crop loss.

    100 %
    50 %
    Source: Oerke, E. C. »Crop losses to pests.«
    Journal of Agricultural Science144 (2006): 31–43.

    Without the use of herbicides, massive crop loss would result due to pests, diseases and weeds. Current crop protection can reduce potential crop loss of corn by about:

    • Setaria faberii
    • Diabrotica virgifera

Visit the Clariant Crop Solutions Lab

Taking Crop Protection
to a higher level

»The Synergen™ product range is giving the entire crop-spraying sector a new quality by providing sustainable tools for increasing crop yields. As tank-mix adjuvants, they improve spray behavior and foliar uptake of active substances, enabling better control of pests.«

Peter Mansour, Lab Technician
Crop Solutions Research & Development

»Our newest addition is the Synergen™ ME product family, which combines five different adjuvant-based modes of action for boosting the effectiveness of herbicides and plant growth regulators.«


Testing for efficiency

Excellence in
Every Drop


Interview with Prof. Dr. Peter Baur,
Head of Clariant's Crop Solutions Competence Center

The greatest reward is maximizing the yield

The world population is growing. Agricultural areas are limited and even decreasing. Will farmers still be able to increase their yields?
They have to. People need to eat. Farmers will be able to increase their yields, as they have done since they began cultivating grains 10,000 years ago. Enhanced techniques, new crop varieties and recent agricultural chemical developments have helped farmers advance. But agricultural chemistry will need to be reassessed.

Why is a reassessment important?
The use of pesticides and herbicides is becoming more and more regulated—and rightly so, because we all want to produce sustainably. However, if farmers do not use enough of the right crop-protection products, weeds, fungi and insects will survive and start developing resistances. The old saying applies equally to these pests: »What does not kill us makes us stronger.« This will be a huge issue in the coming decades.

Can you give an example?
For a long time, the herbicide glyphosate has been used around the world. More and more weeds are able to shake off anything farmers spray on them and thus continue to grow. Using increased amounts of glyphosate would not solve the problem, and it is not possible for environmental reasons. We certainly need smarter sustainable solutions.

What do you have in mind?
In the Crop Solutions Competence Center at Clariant, we have developed a series of adjuvants under the brand name Synergen™. These adjuvants are biological enhancers of herbicides and pesticides and allow us to take advantage of the full potential of active substances. These additives increase effectiveness, for example, by minimizing the amount of droplets scattered by the wind (drift), by ensuring that plants are wetted more completely and that active ingredients penetrate the leaf more easily.

Does Synergen™ ME counteract the growing glyphosate resistance?
We developed products for the Synergen™ ME family especially for this purpose. In Synergen™ ME, various surfactants provide optimal retention and coverage on the leaf. An additional component causes the texture of the foliar surface to swell, enabling the herbicide to penetrate it much more effectively. We offer different products, which best fit glyphosate.

Are Synergen™ products harmful to the environment?
No, neither their production nor their use is harmful. All Synergen™ adjuvants are primarily produced from bio-based raw materials and are biodegradable.

Prof. Dr. Peter Baur,
Head of Clariant's Crop Solutions Competence Center 

»People need to eat. Farmers will be able to increase their yields, as they have done since man began cultivating grains 10,000 years ago.«


Synergen™  ME at work

Protecting the crop


The Synergen™ ME benefits

An ideal mixture for crop solutions

Good Biodegradability

Synergen™ ME is primarily produced from sustainable resources, is biodegradable and requires no labeling as a hazardous material.

Gentle on

The adjuvant is particularly gentle on crops and can be used with most common herbicides.


It considerably enhances the performance of the active ingredients at lower dosages.

crop loss

Boosted effectiveness of herbicides thanks to a unique combination of five key modes of action.

The Synergen™ ME product family

Eco-friendly, non-hazardous and efficient tank-mix adjuvants

Clariant Image Boock Adriana portrait 2019
Adriana Boock,
Global Marketing Segment Leader
Crop Solutions

»The Synergen™ ME family of products is the latest addition to the product range of Synergen™ tank-mix adjuvants. Synergen™ ME products are made with a special surfactant system, which creates a stable microemulsion under all practical climate conditions.«

»Synergen™ ME products are specially designed to address numerous needs of the farmer. They reduce complexity, as no separate mixing of salt enhancer or wetting agent is needed. Also, they combine and optimize herbicides for better yields and excellent weed control—all in a single product.«

Synergen™ ME


Enhanced weed control made simple:

Methylated seed oil (MSO), ammonium sulfate (AMS) and a special blend of non-ionic surfactants are the key components of Synergen™ ME. Unlike other MSO adjuvants, Synergen™ ME products form a fine emulsion in water, which is highly stable at a broad range of temperatures (-10 °C to 50°C).

The Synergen™ ME microemulsion exhibits excellent stability properties and is compatible with all kinds of agrochemical formulations.

This reduces complexity, while increasing flexibility and security for farmers when mixing components in the spray tank.

The advantages of Synergen™ regarding drift, retention, water conditioning, penetration and coverage are explained below. Additional benefits include:
  • prevention of active recrystallization from the spray deposit
  • reduction of the amount of active ingredient lost by volatility
  • suitability for low-volume spray applications
  • Less drift


    Unwanted spray drift of agrochemical droplets can be worsened by adjuvants present within the agrochemical formulation and/or by the addition of certain tank-mix adjuvants. Synergen™ ME has been extensively tested in agrochemical spray applications. The results have shown that some Synergen™ ME products cause no increase in driftable droplets, while others may be considered efficient and effective drift retardant products. Synergen™ ME spray solutions reduce drift loss, regardless of adjuvant type and concentration, even with the presence of fertilizer salts in the spray tank.

    No negative impacts on drift


    Flat fan Nozzle: XR110-02

    Tap water

    Synergen™ ME 0.5%

    Glyphosate SL

    Glyphosate SL + Synergen™ ME 0.5%

    2,4 D SL

    2,4 D SL + Synergen™ ME 0.5%

    (Pressure: 3 bars)

    Drift management


    air injection nozzle: ID120-02

    Tap water

    Synergen™ ME 0.5%

    (Pressure: 3 bars)

    Independent of spray nozzle


    different nozzles:

    XR110-02 Synergen™ ME

    LU120-02 Synergen™ ME

    ID120-02 Synergen™ ME

    AD120-04 Synergen™ ME

    XR110-02 Tap water

    LU120-02 Tap water

    ID120-02 Tap water

    AD120-04 tap water

    (Pressure: 3 bars)

  • Reduced bounce-off


    Retention and spray droplet adhesion are key factors when aerial agrochemical spray applications are used. Retention not only depends on several features of the plant leaf surface, but also on the agrochemical formulation and the presence of tank-mix adjuvants. Agrochemical spray applications containing Synergen™ ME products exhibit excellent retention profiles that protect agrochemical spray droplets from bouncing off onto the ground.

    Synergen™ ME is a substantial progress for increasing formulation compatibility without sacrificing any efficiency by deactivating the active ingredient with antagonistic salts (i.e. calcium).

    L to R: Water, standard commercial agrochemical formulation, standard commercial agrochemical formulation with 0.5% of a Synergen™ ME product
  • Perfect placement


    Spray applications containing Synergen™ ME exhibit good retention and optimized leaf coverage for systemic herbicides, which is essential for weed-control performance.

  • Adding water-conditioning agent?


    Synergen™ ME is a substantial progress for increasing formulation compatibility without sacrificing any efficiency. Whereas MSO adjuvants, non-ionic surfactants and water-conditioning agents are added separately to the spray tank in a two- to three-step process, Synergen™ ME already contains all three components. Additional proof points include the following:

    • Adding an MSO adjuvant, i.e., without a water-conditioning agent, only slightly increased the penetration of both actives.
    • Using a fully adjuvanted formulation (OD formulation) is a sound solution and adds increased efficiency than mere actives and MSO adjuvants alone.
    • Adding Synergen™ ME not only considerably improved the penetration levels of mesotrione and nicosulfuron, but also outperformed those formulations that include the MSO adjuvant and the fully adjuvanted OD formulation.
    • Formulations using Synergen™ ME were significantly more effective thanks to an optimized combination of AMS and MSO that simultaneously protects and boosts weak acid herbicides such as mesotrione and nicosulfuron.

    Cuticular penetration of Nicosulfuron


    Nicosulfuron WG75

    Nicosulfuron WG75 + MSO Adjuvant

    Nicosulfuron OD

    Nicosulfuron WG75 + Synergen™ ME (0.5%)

    Cuticular penetration of mesotrione


    Mesotrione SC480

    Mesotrione SC480 + MSO Adjuvant

    Mesotrione OD

    Mesotrione SC480 + Synergen™ ME (0.5%)

  • Getting inside the surface


    Once water has evaporated from the spray droplet, the spray deposit is formed. Now the oil (MSO) and the non-ionic surfactants present in Synergen™ ME begin to take effect. MSO swells the waxy and scarcely permeable cuticle, allowing the herbicide to enter the weed more rapidly and at higher concentrations. A special component of the surfactant blend prevents the active from recrystallizing and helps maintain the agrochemical in its best physical state for penetration to occur over days. Additional proof points include the following:

    • The penetration levels of dicamba acid into plant cuticles depend on the water quality present.
    • As dicamba is an acid herbicide, the presence of antagonistic ions can have a negative impact on its performance.
    • Dicamba in extremely hard water (EHW, 1300 ppm CaCO3) is bound by excess calcium ions (more than in tap water), which hinders its penetration.
    • Dicamba penetration levels in EHW only reached 0.24% and 2.5% of the amount after 6 hours and 12 hours respectively.
    • The addition of Synergen™ ME immediately provided significant penetration improvement of dicamba.
    • Synergen™ ME was also added to EHW (0.5% w/w) and after 6 hours, the rate of penetration was 50 times faster than dicamba in EHW.
    • Synergen™ ME not only deactivated the antagonistic salts in the test solutions, but the methylated oil in the products significantly enhanced the cuticular penetration of dicamba.
    • The water-conditioning and penetration-enhancement effects are still present at a similar performance level compared to other MSOs or non-ionic surfactants plus 5% AMS (graphic on the right).

    Cuticular penetration of Dicamba after 12 hours


    14C dicamba (Extremely hard water)

    14C dicamba (Tap water)

    + Adjuvant ME

    Cuticular penetration of Dicamba after 24 hours


    + Adjuvant ME (0.5%)

    + NIS (0.3%) + AMS

    + MSO Adjuvant B (0.5%) + AMS

    14C dicamba (extremely hard water)

Performance Check


Synergen™ ME significantly improved the field performance of a leading sulfonylurea herbicide. In a field trial carried out on wheat, no crop tolerance issues were observed in any of the four replicates. This tank mix adjuvant was able to further enhance the fully adjuvanted sulfonylurea formulation.

Increasing Weed Control

Decreasing weed population


Want to know more?


We’d really like to hear from you. Please give us a call
or use the contact form below if you have any questions or would like
more information about Synergen™.

Bob Condon
Bob Condon
Contact Person
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Solutions. Synergen™ GL 5.
Synergen™ GL 5 is a polyglycerol ester based adjuvant which is derived from renewable resources. Learn more
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