VitiPure HCO
VitiPure HCO is obtained by hydrogenation of castor oil. Hydrogenated castor oil is vegetable origin (castor oil) and is hydrophobic in nature. VitiPure HCO is in powder form intended for solid oral and topical use. At room temperature it is a fine milled solid powder with a high melting point (>80°C). In solid oral dose formulations, VitiPure HCO is applied as hydrophobic lubricant and as sustained release agent in solid oral formulations. In topical preparations, VitiPure HCO is used as viscosity enhancer and as consistency factor.
Informations sur le produit
- Manufactured according to IPEC GMP
- Complies to EP and USP
- Consistent particle size (d50~ 20 µm) distribution, ideal as tablet lubricant where hydrophobic lubricant is desired.
- Ideal for direct compression and dry granulation process
- Hydrogenated castor oil powder
- API release modifier
- Tablet lubricant
- Consistency factor
Various APIs formulated in oral tablet form with hydrogenated castor oil as lubricant or modified release agent are as follows: Clopidogrel, Benazepril, Misoprostol, Ropinirole, Felodipine, Diclofenac, Hydrochlorothiazide, Tadafil, Cefuroxime etc.
Other APIs formulated in topical form with hydrogenated castor oil as consistency factor are as follows: Lidocaine, Prilocaine, Betamethasone, Calcipotriene, Urea, Tacalcitol, Hydrocortisone, Minocycline, Glycyrrhetinic etc.
Solid, white milled powder
Ph. Eur: Castor oil, hydrogenated; USP: Hydrogenated castor oil
- IPEC GMP Pharma Grade
- EP / USP
Germany
20kg pack size (PE bag in carton box); Sample size 0.5kg
- Particle size distribution
- d10: 2 to 4 µm
- d50: 16 to 24 µm
- d90: 55 to 85 µm
- VitiPure™ HCO is practically insoluble in water, slightly soluble in methylene chloride, very slightly soluble in anhydrous ethanol and practically insoluble in petroleum.
