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Excipientes para os Serviços de Saúde
Solubilizantes para aplicações comuns

Cerca de 40% das novas entidades químicas inventadas como possíveis IFAs relevantes para doenças são pouco hidrossolúveis e não podem ser absorvidas de forma eficaz no trato gastrointestinal por causa de suas complexas estruturas químicas ou perfis de absorção, o que faz com que não sejam eficazes. Isso aumenta o ônus para as empresas farmacêuticas não apenas no aspecto financeiro, mas também na perda de vantagem competitiva e no tempo de lançamento no mercado. A baixa biodisponibilidade dos IFAs não é apenas responsável pela redução da eficácia dos medicamentos, mas pode também causar efeitos colaterais indesejáveis após serem ministrados.

Como a Clariant poderia ajudá-lo a obter uma solução? Oferecemos uma grande variedade de solubilizantes que aumentam o desempenho dos IFAs

  • PEGs
  • Derivados de PEG

Os formuladores farmacêuticos podem aumentar a biodisponibilidade do Ingrediente Farmacêutico Ativo (IFA) usando excipientes que melhoram a solubilidade com o benefício de reduzir o tempo de lançamento no mercado

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