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Methyl Oxirane polymer with Oxirane

VitiPure P 188 MG

VitiPure P 188 MG is all rounder non-ionic polymer suitable for various pharmaceutical applications. It is supplied as a white to slightly yellowish flakes/powder with a waxy consistency. It is freely soluble in ethanol and water (opalescent solution). It is used as a wetting agent, emulsifier, solubilizer and bioavailability enhancer of poorly soluble APIs. It is typically used into formulations such as Topicals (Cream, Hot processing, Cold processing, Foam, Gel), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Instant release, extended release, matrix-type system, Reservoir-type system, Film), Liquid preparations (Solution). 

Generic name: Poloxamer 188 (Ph. Eur., USP/NF)

Benefits
  • It used as wetting agents, as emulsifiers and solubilizers
  • It improves the solubility, absorption and bioavailability of low-solubility actives
  • Suitable in solid dispersions and improves the solubility, absorption and bioavailability of low-solubility APIs in solid oral dosage forms.
  • Versatile solubilizer suitable to use in solid, semi-solid and liquid formulations
Product details
Chemical Name
  • Methyl Oxirane polymer with Oxirane
Product Function
  • Solublizers
  • Plasticizers
  • Emulsifier
Applications
VitiPure P 188 is a non-ionic, hydrophilic emulsifier and/or solubilizer for pharmaceutical preparations. Applied in formulations such as Skin Delivery, Softgels, Solubilization.
Generic Name
Poloxamer 188 (Ph. Eur., USP/NF)
Grade
IPEC GMP Pharma Grade 
Country of Origin
Spain
Manufacturer address
Clariant Ibérica Producción S.A., Autovía Tarragona-Salou, Km. 3,8, 43110 La Canonja Tarragona, Spain
Packaging size (Article Nr.)
100kg steel drum (Article Nr. 32217113215, 32217113216) and 25kg steel drum (Article Nr. 32217129285); Sample size 0.5kg
Retest period
24 months

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VitiPure P 188 MG

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