Unlock the secrets of healthy aging

with an avant-garde active ingredient


New seaweed-based active Epseama® pioneers the targeting of long non-coding RNA 886 to rejuvenate skin self-renewal and self-defense abilities and preserve skin youth. It offers Personal care formulators the key to a unique evolution in anti-aging.



Clariant Active Ingredients recently focused its research on a long non-coding RNA, called “nc886”. This RNA was recently recognized to be a key regulator of PKR, a protein known for inducing premature aging. For the first time, the correlation between aging and decrease of nc886 expression was demonstrated. Therefore, stimulating nc886 becomes a new target for skin rejuvenation. With Epseama, the industry can develop effective skincare products directed at the true causes of aging.

As a recognition for this innovative pathway, Epseama won the second prize at the BSB Innovation Award 2019 in the category "Active Ingredients".


Outstanding performance

Epseama performance is confirmed in clinical trials on women over 50 after only 4 weeks. Difficult to remove nasolabial wrinkes are smoothed - reduced by 19% in volume and 10% in roughness after only four weeks. Spots decreased by 10% and skin moisture levels increased by 14.2%. 


Responsible sourcing

Epseama is an extract of the brown seaweed Laminaria japonica (Kelp or Kombu), known as the "superfood of the sea" thanks to its rich composition in vitamins and minerals. It is farmed off the coast of a South Korean island through sustainable and responsible aquaculture practices. Kelp farming can help maintain a healthy coastal seawater environment.



Mechanism of action

For more information on Epseama and its proven performance in clinical trials visit our product page. To discover our other active ingredients, visit our homepage Clariant Active Ingredients.

Any questions?
Our experts are standing by to offer you more details. Would you like to get in touch with one of them?

Any Questions?

Get in Contact

Catherine Centro
Catherine Centro
Contact Person
This information corresponds to the present state of our knowledge and is intended as a general description of our products and their possible applications. Clariant makes no warranties, express or implied, as to the information’s accuracy, adequacy, sufficiency or freedom from defect and assumes no liability in connection with any use of this information. Any user of this product is responsible for determining the suitability of Clariant’s products for its particular application.<br />
<br />
* Nothing included in this information waives any of Clariant’s General Terms and Conditions of Sale, which control unless it agrees otherwise in writing. Any existing intellectual/industrial property rights must be observed. Due to possible changes in our products and applicable national and international regulations and laws, the status of our products could change. Material Safety Data Sheets providing safety precautions, that should be observed when handling or storing Clariant products, are available upon request and are provided in compliance with applicable law. You should obtain and review the applicable Material Safety Data Sheet information before handling any of these products. For additional information, please contact Clariant.<br />
<br />
* For sales to customers located within the United States and Canada the following applies in addition: No express or implied warranty is made of the merchantability, suitability, fitness for a particular purpose or otherwise of any product or service.<br />
<br />
© Trademark of Clariant registered in many countries.<br />
® 2019 Clariant International Ltd 

You are about to leave the Clariant domain

The link you activated will take you outside the Clariant site in about 10 seconds. If you want to stop this, press "Cancel".

Request to Clariant

Please enter your contact information so we are able to process your request. Thank you for your interest.

Daniela Eiselin
Daniela Eiselin
Contact Person