Safeguarder of the matrisome

Edition Date :
May 18, 2021

Prenylium is a Morus alba tree root extract obtained by the Plant Milking technology allowing the culture of plants in aeroponic condition. This sustainable technology enables the exploration of unsourceable plant part such as roots without destroying tree. In addition, through an innovative process used to stimulate the growth of the roots, the content of targeted molecules is increased: +2000% of prenylated flavonoids in comparison to traditional mulberry roots. This class of bioactive compounds has a higher affinity with cellular membranes and better interaction with biological targets than standard flavonoids: they possess interesting variety of anti-aging activities such as anti-oxidant and immunoprotection.

Prenylium modulates the expression of CCN1, a pivotal gene that affects the synthesis of some of the core elements constitutive of the skin extracellular matrix, such as collagen type I and III and decorin. Doing so, Prenylium protects the skin's core matrisome from degradation while counteracting ECM disorganization that increase with age.

For its mechanism of action and strong clinical results as well as for its sustainable sourcing, Prenylium won 3 prestigious awards in 2020:

  • - the PCHi Fountain Award in the category "Anti-aging"
  • - the BSB Innovation Award in the category "Environment"
  • - the in-Cosmetics Innovation Award in the category "Active Ingredients"
  • To discover our other active ingredients, visit our homepage Clariant Active Ingredients.

After four and eight weeks of application, wrinkles are visibly reduced and skin smoothness is enhanced.
Catherine Centro
Catherine Centro
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Chemical Name
  • Propanediol (and) Water (and) Morus Alba Root Extract
Product Function
  • Active Ingredient
Chemical Type
  • Advanced plant root extract
  • Cream, Lotion
  • Colour Cosmetic
Performance Claims
  • Anti-aging
  • Reduces wrinkles
  • Smoothing

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Prenylium is an active ingredient that can be used in various skincare and cosmetic products, such as:

  • Anti-aging creams
  • Wrinkles smoother
  • Dermal matrix prevention
Technical data

INCI Name: Propanediol, Water, Morus Alba Root Extract

Use level: 1%

Appearance: orange to brown liquid

Origin: root extract from patented Plant Milking technology - France

Certification: Cosmos approved

Compliance: China IECIC listed, Plant origin, Nagoya Protocol compliant

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Catherine Centro
Catherine Centro
Contact Person