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Home / Products & Industries / Products / Celyscence, the senescence preventer for healthy a…
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The senescence preventer for healthy aging

Celyscence™

Edition Date :
February 06, 2026

Celyscence™ is an extract of the seedless milk thistle flower (Sylibum marianum) that prevents the accumulation of senescent cells (also called "zombie cells") in the skin thanks to three different activities:

1- Prevention of cellular senescence 

2- Senolytic effect: activation of the apoptosis process in senescent cells to eliminate them 

3- Senomorphic effect: turning back the phenotype of senescent cells into younger cells, thus preventing them from producing SASPs, some deleterious molecules that cause senescence in surrounding cells 

Thanks to this triple mode of action, Celyscence™ restores skin healthiness, which was demonstrated on clinical studies: on the chest, wrinkles are decrease and luminosity is increased, to help women feel more confident in their femininity. On the face, melanin content was reduced to increase skin brightness.

Celyscence™ received the BSB Innovation Awards 2021 (2nd prize) and the Ringier Technology Innovation Awards 2021.

Celyscence_Award_BSB-200x200Celyscence_Award_Ringier-white-200x200
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Product Information

Benefits

After 56 days, décolleté hydration is increased by 14% and brightness by 3.2%. After only 28 days, the neck is visibly firmer, smoother, and facial contours are remodeled.

After 14 days, melanin content on the face is decreased by 5.4%.

Product information
Applications
  • Anti-aging
  • Complexion and Brightening
Categories:
Active Ingredients
Compliances:
  • China compliance
  • Preservative Free
  • Cosmos Approved
INCI:
Glycerin (and) Water (and) Silybum Marianum Extract
Origin:
Extract of milk thistle flowers hand harvested in South Korea
Technologies:
Botanical
  • Anti-aging creams
  • Neck firming cream
  • Décolleté complexion boosters
  • China / IECIC listed
  • NMPA registered
  • Cosmos approved
  • ISO 16125 Natural Origin Content = 1 

Documentation

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Product Video

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