Celyscence™

The senescence preventer for healthy aging

Edition Date :
April 19, 2021

Celyscence is an extract of the seedless milk thistle flower (Sylibum marianum) that prevents the accumulation of senescent cells (also called "zombie cells") in the skin thanks to three different activities:

1- Celyscence prevents cells from becoming senescent

2- Celyscence activates the apoptosis process in senescent cells to eliminate them (senolytic effect)

3- Celyscence turns back the phenotype of senescent cells into younger cells, thus preventing them from producing SASPs, some deleterious molecules that cause senescence in surrounding cells (senomorphic effect)

Thanks to this triple mode of action, Celyscence restores skin healthiness, which was demonstrated on clinical studies: on the chest, wrinkles are decrease and luminosity is increased, to help women feel more confident in their femininity. On the face, melanin content was reduced to increase skin brightness.

To discover our other active ingredients, visit our homepage Clariant Active Ingredients.

Benefits

After 56 days, décolleté hydration is increased by 14% and brightness by 3.2%. After only 28 days, the neck is visibly firmer, smoother, and facial contours are remodeled.

After 14 days, melanin content on the face is decreased by 5.4%.

Catherine Centro
Catherine Centro
Contact Person

Request to Clariant

Order Sample Print this page
Documents

Download File

Please enter your contact details and the file will start downloading immediately after your details have been submitted. This only has to be done for the first file you download on this site. Thank you for your understanding.

Personal Information

Celyscence™

Please choose one of the available product configurations:
No files are available for this product.
Applications

Celyscence is an active ingredient that can be used in various skincare and cosmetic products, such as:

  • Anti-aging creams
  • Neck firming cream
  • Décolleté complexion boosters
Technical data

INCI Name: Glycerin, Water, Silybum Marianum Extract

Use level: 1-5%

Appearance: yellow to slightly brown liquid

Compliance: China IECIC listed, Plant origin

Request to Clariant

Please enter your contact information so we are able to process your request. Thank you for your interest.

Catherine Centro
Catherine Centro
Contact Person
Disclaimer:
This information corresponds to the present state of our knowledge and is intended as a general description of our products and their possible applications. Clariant makes no warranties, express or implied, as to the information’s accuracy, adequacy, sufficiency or freedom from defect and assumes no liability in connection with any use of this information. Any user of this product is responsible for determining the suitability of Clariant’s products for its particular application.<br />
<br />
* Nothing included in this information waives any of Clariant’s General Terms and Conditions of Sale, which control unless it agrees otherwise in writing. Any existing intellectual/industrial property rights must be observed. Due to possible changes in our products and applicable national and international regulations and laws, the status of our products could change. Material Safety Data Sheets providing safety precautions, that should be observed when handling or storing Clariant products, are available upon request and are provided in compliance with applicable law. You should obtain and review the applicable Material Safety Data Sheet information before handling any of these products. For additional information, please contact Clariant.<br />
<br />
* For sales to customers located within the United States and Canada the following applies in addition: No express or implied warranty is made of the merchantability, suitability, fitness for a particular purpose or otherwise of any product or service.<br />
<br />
© Trademark of Clariant registered in many countries.<br />
® 2019 Clariant International Ltd 

You are about to leave the Clariant domain

The link you activated will take you outside the Clariant site in about 10 seconds. If you want to stop this, press "Cancel".