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Health Care

Excipients to enhance medicines

Trusted Pharmaceutical Excipients: Quality, Expertise, and Regulatory Excellence

Clariant delivers a comprehensive portfolio of pharmaceutical excipients under the brands VitiPure, Polyglykol, Motusflex and Lanogen backed by extensive technical production expertise and regulatory know-how. Our stringent adherence to IPEC Good Manufacturing Practices and robust documentation for EMA/FDA compliance has established Clariant as a trusted provider of quality excipients in the healthcare industry, with pharmaceutical manufacturers worldwide relying on our consistent, high-performance ingredients for their most demanding formulation challenges.

Clariant Healthcare functional Excipients by Application

Enhancing Oral Drug Delivery

Clariant's specialized excipients optimize oral formulations for improved performance, stability, and processing efficiency. Our portfolio includes pharmaceutical-grade Polyglykol (PEG) products, functional polymers, and other solubilizers (VitiPure) that address key challenges in modern oral drug development. With decades of expertise in pharmaceutical ingredients, we partner with you to enhance tablet disintegration, improve API solubility, and ensure consistent manufacturing of oral dosage forms that meet stringent regulatory requirements.

Advanced Solutions for Injectable Formulations

Safety meets performance in Clariant's parenteral-grade ingredients. Our VitiPure Superior highly purified excipients for sensitive APIs, and selected VitiPure LEX low endotoxin excipients are designed specifically for injectable applications. From solubilizers that enhance bioavailability to functional ingredients that improve formulation characteristics, our solutions help you develop safer, more effective parenteral products while navigating the complex regulatory landscape of injectable pharmaceuticals.

Enabling Next-Generation Biopharmaceuticals

Clariant's biopharma solutions address the unique challenges of biological drug development. Our specialized PEG derivatives and functional excipients protect sensitive biomolecules and enhance stability during processing and storage. With high-quality ingredients for PEGylation, buffer formulation, and stabilization, we support your innovation from early development through commercial manufacturing, helping bring life-changing biotherapeutics to patients worldwide.

Innovative Ingredients for Dermal Applications

Transform your topical formulations with Clariant's comprehensive range of functional ingredients. From Motusflex rheology modifiers that create the perfect texture to high-performance emulsifiers and solubilizers, our solutions combine performance with sensory excellence. Our ingredients support various applications—from prescription medications to OTC products—delivering the stability, compatibility, and patient-friendly properties that define successful topical pharmaceuticals.

Explore our expertise in 8 focus fields

Control Release
Polyglykol, Vitipure™ HCO: Dissolution rate modification
Raw Materials for PEG Lipids and Functional PEGs
Polyglykol, Vitipure™ HCO: Dissolution rate modification
Tableting Aids for Direct Compression
Polyglykol, Vitipure™ P, HCO: Continuous manufacturing, cost saving compared to wet granulation
Rheology Modifiers
MotusFlex™: Viscosity enhancement with exeptional sensorial effect
Counter Ion
VitiPure™ NMG: Solubility and bioavailabillity enhancement
Preservation
VitiPure™ PARABENS, PHENOXETOL, BHT: Preservatives and Antioxidants
Solubilizers for Standard Applications
Polyglykol, Vitipure™ P, O, L, HCO, CO, HS: Solubility enhancement
Solubilizers for High-Risk Applications
VitiPure LEX ™, VitiPure ™ SUPERIOR: Low bioburden, low elemental impuritiescfor sensitive APIs

Related products

  • Solubilizers for Standard Applications
    Wide range of solubilizers that will increase the API performance Polyethylene Glycols & PEG-Derivatives
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  • Solubilizers for High-Risk Applications
    Wide range of low bioburden and low elemental impurities parenteral excipients for sensitive APIs: Polyethylene Glycols & PEG-Derivatives
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  • Control Release Excipients
    Wide range of excipients that supports the dissolution rate modification of APIs: Polyethylene Glycols & PEG-Derivatives
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  • Raw Materials for PEG Lipids and Functional PEGs
    We offer multiple molecular weight Methoxy Polyethylene Glycols (mPEGs) as starting raw material for development of PEG-Lipids to create hydration shell around LNPs.
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  • Direct Compression Excipients
    Wide range of direct compression excipients to enable continuous manufacturing & facilitates cost saving compared to wet granulation
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  • Rheology Modifiers Excipients
    Wide range of rheology modifiers targeting viscosity requirements of high or low viscous formulations: Synthetic Cross-linked Polymers
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  • Counter Ion Excipients
    We offer meglumine to effectively increase the solubility and bioavailability enhancement of APIs
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  • Preservation Excipients
    Wide range of preservatives to effectively control the microbial bioburden of the formulation: Parabens, Phenoxetol and Antioxidant
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  • VitiPure CO 35
    VitiPure CO 35 is a non-ionic solubiliser and emulsifying agent for the human and veterinary pharmaceutical industries. It is made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. At room temperature it appears as pale-yellow oily liquid. It forms clear solutions in water. It is typically used into formulations such as Topicals (Cream, Hot processing), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Soft shell capsules, Tablets, Instant release), Liquid preparations (Solution).
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  • VitiPure CO 35 LEX
    VitiPure CO 35 is a non-ionic solubiliser and emulsifying agent for the human and veterinary pharmaceutical industries. It is made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. At room temperature it appears as pale-yellow oily liquid. It forms clear solutions in water. The LEX grade represents Low Endotoxins & Low bioburden grade product especially suitable for customers using it in high-risk applications.
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  • VitiPure CO 35 Superior
    VitiPure CO 35 Superior is a non-ionic solubilizer and emulsifying agent for human and veterinary pharmaceutical markets. It is manufactured by ethoxylating castor oil in a molar ratio of 1:35. VitiPure CO 35 Superior is then purified with a patented process to reduce residual impurities yielding transparent almost colorless oily liquid which forms clear solutions in water. Typically used in sensitive applications where final formulations need to be colorless, or the API is sensitive to residual impurities. And where the end formulation needs to have low microbial load with low endotoxins.
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  • VitiPure HCO 40
    VitiPure HCO 40 is versatile non-ionic solubilizer and emulsifier enhancing the solubility and bioavailability of hydrophobic APIs and fat-soluble vitamins. VitiPure HCO 40 is obtained by reacting 40 moles of ethylene oxide with 1 mole of hydrogenated castor oil. At the room temperature it appears as white to yellowish paste. VitiPure HCO 40 is suitable for SEDDS and SMEDDS. It is typically used into formulations such as Topicals (Cream, Hot processing), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Soft shell capsules, Tablets, Instant & modified release), Liquid preparations (Solution).
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  • VitiPure HCO 40 LEX
    VitiPure HCO 40 is versatile non-ionic solubilizer and emulsifier enhancing the solubility and bioavailability of hydrophobic APIs and fat-soluble vitamins. VitiPure HCO 40 is obtained by reacting 40 moles of ethylene oxide with 1 mole of hydrogenated castor oil. At the room temperature it appears as white to yellowish paste. VitiPure HCO 40 is suitable for SEDDS and SMEDDS. The LEX grade represents Low Endotoxins & Low bioburden grade product especially suitable for customers using it in high-risk applications.
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  • VitiPure L 20
    VitiPure L 20 is a non-ionic, hydrophilic emulsifier, co-emulsifier and solubilizer. It is an oily, yellow or brownish-yellow, clear or slightly opalescent liquid with a faint odor. VitiPure L 20 can be used in various pharmaceutical formulations. It is typically used into formulations such as Topicals (Cold processing, Hot processing, Cream, Emulsion, Foam, Gel), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Soft shell capsules, Tablets, Instant release), Liquid preparations (Solution, Suspension) and Suppositories.
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  • VitiPure L 20 LEX
    VitiPure L 20 is a non-ionic, hydrophilic emulsifier, co-emulsifier and solubilizer. It is an oily, yellow or brownish-yellow, clear or slightly opalescent liquid with a faint odor. VitiPure L 20 can be used in various pharmaceutical formulations. The LEX grade represents Low Endotoxins & Low bioburden grade product especially suitable for customers using it in high-risk applications.Generic name: Polysorbate 20
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  • VitiPure LEX 300
    VitiPure LEX 300 is a low molecular weight polyethylene glycol excipient type of the VitiPure LEX range for sensitive APIs and formulations. With defined microbiological and endotoxin checks of the final packed product batch, which are given individually on the certificate of analysis, we would like to support you in your individual formulation risk assessment.
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  • VitiPure LEX 400
    VitiPure LEX 400 is a low molecular weight polyethylene glycol excipient type of the VitiPure LEX range for sensitive APIs and formulations. With defined microbiological and endotoxin checks of the final packed product batch, which are given individually on the certificate of analysis, we would like to support you in your individual formulation risk assessment.
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  • VitiPure Meglumine LEX
    VitiPure Meglumine LEX improves the solubility and bioavailability of APIs. Meglumine is a multi-talented functional excipient which is used as a counter-ion to form a salt with the API, or as a standard excipient to modify the pH to enhance the API solubility and stability. Traditionally, Meglumine is used as a counter-ion in contrast media. Applications include oral solid, and liquid formulations. And, widely used in sensitive formulations where low bioburden and low endotoxin grade is required.
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  • VitiPure O 80
    VitiPure O 80 is a non-ionic, hydrophilic emulsifier, co-emulsifier, solubilizer and suspension stabilizer used widely in various biopharmaceutical formulations. It appears as amber liquid in room temperature with a faint characteristic odor. VitiPure O 80 has a broad working pH range and offers good skin tolerance. It is typically used into formulations such as Topicals (Cold processing, Hot processing, Cream, Emulsion, Foam, Gel, Hydrophilic ointment, Lipophilic ointment), Solid orals (Hot melt extrusion, Spray drying, Conventional pellets, Hard shell capsules, Multiple-unit tablets, Single-unit tablets, Soft shell capsules, Tablets, Enteric release, Instant release, Aqueous Coating), Liquid preparations (Solution, Suspension) and Suppositories.Generic name: Polysorbate 80
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  • VitiPure O 80 LEX
    VitiPure O 80 is a non-ionic, hydrophilic emulsifier, co-emulsifier, solubilizer and suspension stabilizer used widely in various biopharmaceutical formulations. It appears as amber liquid in room temperature with a faint characteristic odor. VitiPure O 80 has a broad working pH range and offers good skin tolerance. The LEX grade represents Low Endotoxins & Low bioburden grade product especially suitable for customers using it in high-risk applications. Generic name: Polysorbate 80
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  • VitiPure O 80 Superior
    VitiPure O 80 Superior is a non-ionic solubilizer and emulsifying agent for human and veterinary pharmaceutical markets. It is manufactured by ethoxylating sorbitan mono-oleate in a molar ratio of 1:20. VitiPure O 80 Superior is then purified with a patented process to reduce residual impurities yielding a transparent almost colorless oily liquid. Typically used in sensitive formulations where final formulations need to be colorless, or the API is sensitive to residual impurities. And, where the end formulation needs to have low microbial load with low endotoxins.
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  • VitiPure P 188 MG
    VitiPure P 188 MG is all rounder non-ionic polymer suitable for various pharmaceutical applications. It is supplied as a white to slightly yellowish flakes/powder with a waxy consistency. It is freely soluble in ethanol and water (opalescent solution). It is used as a wetting agent, emulsifier, solubilizer and bioavailability enhancer of poorly soluble APIs. It is typically used into formulations such as Topicals (Cream, Hot processing, Cold processing, Foam, Gel), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Instant release, extended release, matrix-type system, Reservoir-type system, Film), Liquid preparations (Solution). Generic name: Poloxamer 188 (Ph. Eur., USP/NF)
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  • Motusflex HV
    Motusflex HV is a high viscosity rheology modifier & synthetic polymer used as a gelling agent for aqueous systems and as a texturizer and thickener for oil-in-water emulsions. Motusflex HV provides formulations with excellent yield value, corresponding to superior stability even in the absence of additional emulsifier. This product has a good compatibility with APIs and organic solvents (ethanol, acetone) and is stable towards UV radiation and high shear stress.
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  • Motusflex MF
    Motusflex MF is a multi-functional rheology modifier & synthetic polymer which offers the solution for complex skin formulations – a true partner which suits your specific requirements. Motusflex™ MF is ready to use and easy to add at any formulation stage as it disperses quickly in the water or oil phase. It is easy to add Motusflex MF at any formulation step (oil or water phase) and cold processable.
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  • Motusflex LV
    Motusflex LV is a low viscosity rheology modifier & synthetic polymer. Motusflex LV consists of a large, hydrophilic portion and a smaller hydrophobic portion. This chemical structure allows this copolymer to function as primary emulsifier and stabilizer in oil-in-water emulsions. This is done as the hydrophobic portion adsorbs at the oil-water interface, and the hydrophilic portion swells in the water phase to provide exceptional emulsion stability to a broad range of oils. In combination with other polymers like Motusflex HV, Motusflex LV can be used to modify skin rheology and texture, improve pick up as well as to reduce the total amount of required thickener. It is indicated for low-viscosity formulations like lotions, wet wipes, sprayable formulations, hot and cold O/W formulations with an elegant and rich skin after-feel.
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  • Polyglykol 200 USP
    Polyglykol 200 USP is a liquid PEG excipient grade product, produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below).
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  • Polyglykol 300*
    Polyglykol 300 is a liquid PEG excipient grade product, produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 400*
    Polyglykol 400 is a liquid PEG excipient grade product, produced under IPEC GMP conditions.It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 600*
    Polyglykol 600 is a liquid PEG excipient grade product, produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 1000*
    Polyglykol 1000 is a pasty PEG excipient grade product, produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below).Pharmacopoeia name: USP-NF: Polyethylene glycol 1000, Ph. Eur.: Macrogol 1000 * only in combination with a Pharma CoA
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  • Polyglykol 1500 fl*
    Polyglykol 1500 fl is a pasty PEG excipient grade product, produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 1500 S*
    Polyglykol 1500 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 2000 S*
    Polyglykol 2000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 3000 S*
    Polyglykol 3000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 3000 P*
    Polyglykol 3000 P is a milled PEG excipient grade powder product, produced under IPEC GMP conditions. The powder form supports the homogeneous mixing with other materials within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 4000 PF*
    Polyglykol 4000 PF is a milled PEG excipient grade powder product with a fine particle size distribution, produced under IPEC GMP conditions. The powder form supports the homogeneous mixing with other materials within production. The fine particle size distribution supports granulation and compressing processes. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 6000 S*
    Polyglykol 6000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 6000 P*
    Polyglykol 6000 P is a milled PEG excipient grade powder product, produced under IPEC GMP conditions. The powder form supports the homogeneous mixing with other materials within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 6000 PF*
    Polyglykol 6000 PF is a milled PEG excipient grade powder product with a fine particle size distribution, produced under IPEC GMP conditions.The powder form supports the homogeneous mixing with other materials within production. The fine particle size distribution supports granulation and compressing processes. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 8000 S*
    Polyglykol 8000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 8000 P*
    Polyglykol 8000 P is a milled PEG excipient grade powder product, produced under IPEC GMP conditions. The powder supports the homogeneous mixing with other materials within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 8000 PF*
    Polyglykol 8000 PF is a milled PEG excipient grade powder product with a fine particle size distribution, produced under IPEC GMP conditions.The powder form supports the homogeneous mixing with other materials within production.The fine particle size distribution supports granulation and compressing processes. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 10000 S*
    Polyglykol 10000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 12000 S*
    Polyglykol 12000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 20000 P*
    Polyglykol 20000 P is a milled PEG excipient grade powder product, produced under IPEC GMP conditions. The powder form supports the homogeneous mixing with other materials within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 20000 S*
    Polyglykol 20000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Polyglykol 35000 S*
    Polyglykol 35000 S is a flaked PEG excipient grade product, produced under IPEC GMP conditions. The flaked form enables easier handling of the material within production. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). * only in combination with a Pharma CoA
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  • Lanogen™ 1500
    Lanogen™ 1500 is a mixture of Polyglykol 300 and 1500 in a 50 :50 ratio, which is produced under IPEC GMP conditions. It is specified according to the requirements of the main international ICH guidelines and monographs (see below). This ready-made mixture eases the production of ointments.
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