Atención médica: excipientes
Excipientes para mejorar los medicamentos
Trusted Pharmaceutical Excipients: Quality, Expertise, and Regulatory Excellence
Clariant delivers a comprehensive portfolio of pharmaceutical excipients under the brands VitiPure, Polyglykol, Motusflex and Lanogen backed by extensive technical production expertise and regulatory know-how. Our stringent adherence to IPEC Good Manufacturing Practices and robust documentation for EMA/FDA compliance has established Clariant as a trusted provider of quality excipients in the healthcare industry, with pharmaceutical manufacturers worldwide relying on our consistent, high-performance ingredients for their most demanding formulation challenges.
Advanced Solutions for Injectable Formulations
Safety meets performance in Clariant's parenteral-grade ingredients. Our VitiPure Superior highly purified excipients for sensitive APIs, and selected VitiPure LEX low endotoxin excipients are designed specifically for injectable applications. From solubilizers that enhance bioavailability to functional ingredients that improve formulation characteristics, our solutions help you develop safer, more effective parenteral products while navigating the complex regulatory landscape of injectable pharmaceuticals.
Enabling Next-Generation Biopharmaceuticals
Clariant's biopharma solutions address the unique challenges of biological drug development. Our specialized PEG derivatives and functional excipients protect sensitive biomolecules and enhance stability during processing and storage. With high-quality ingredients for PEGylation, buffer formulation, and stabilization, we support your innovation from early development through commercial manufacturing, helping bring life-changing biotherapeutics to patients worldwide.
Enhancing Oral Drug Delivery
Clariant's specialized excipients optimize oral formulations for improved performance, stability, and processing efficiency. Our portfolio includes pharmaceutical-grade Polyglykol (PEG) products, functional polymers, and other solubilizers (VitiPure) that address key challenges in modern oral drug development. With decades of expertise in pharmaceutical ingredients, we partner with you to enhance tablet disintegration, improve API solubility, and ensure consistent manufacturing of oral dosage forms that meet stringent regulatory requirements.
Innovative Ingredients for Dermal Applications
Transform your topical formulations with Clariant's comprehensive range of functional ingredients. From Motusflex rheology modifiers that create the perfect texture to high-performance emulsifiers and solubilizers, our solutions combine performance with sensory excellence. Our ingredients support various applications—from prescription medications to OTC products—delivering the stability, compatibility, and patient-friendly properties that define successful topical pharmaceuticals.
Explore our expertise in 8 focus fields
Growing demand for controlled release formulations reflects the need for enhanced patient comfort across diverse APIs. These formulations reduce dosing frequency—benefiting pediatric and geriatric patients especially—while increasing bioavailability and minimizing side effects. Clariant offers specialized PEGs and PEG-derivatives that precisely modify API dissolution rates, supporting effective product lifecycle extension through reformulation.
Counterions enhance drug solubility by forming dissociable salts that improve bioavailability. Clariant's pharmaceutical-grade Meglumine serves as an effective counterion for anionic APIs (pKa < 6), offering versatile functionality beyond its traditional use in contrast media. As both a salt-forming agent and functional excipient, Meglumine enhances API solubility and stability while providing precise pH adjustment for optimal pharmaceutical formulations.
Oral dosage forms remain dominant in pharmaceutical delivery, with direct compression technology revolutionizing tablet manufacturing. Clariant's specialized PEGs and PEG-derivatives enhance flowability and compressibility while supporting continuous manufacturing processes. Our excipients maintain tablet quality even with high API loads, offering pharmaceutical manufacturers a simplified, cost-effective alternative to wet granulation methods.
Pharmaceutical formulations require effective preservation systems to protect against microbial contamination and to maintain product integrity over time. Ideal preservatives are stable across a broad pH range, non-sensitizing, non-toxic, and effective at low concentrations against a wide spectrum of microorganisms.
Clariant offers a comprehensive range of preservatives (produced under ISO 9001) designed to control microbial bioburden. Our solutions are precisely formulated to deliver optimal antimicrobial efficacy at application-appropriate concentrations, tailored to meet the specific needs of your products.
The mRNA revolution has dramatically expanded therapeutic possibilities across multiple disease areas. Lipid Nanoparticles (LNPs) are crucial for protecting and delivering mRNA, with PEG-Lipids providing essential stabilization. Clariant supplies pharmaceutical-grade Methoxy Polyethylene Glycols (mPEGs) as key starting materials for PEG-Lipid development and protein PEGylation, supporting innovative RNA therapies and vaccines with enhanced circulation time and stability.
Pharmaceutical formulators require precise rheological control for topical applications. Clariant's Motusflex polymers, manufactured under GMP conditions, deliver exceptional batch consistency with defined impurity profiles. These pre-neutralized, synthetic cross-linked polymers simplify processing while providing scalability from R&D to production. Our rheology modifiers achieve targeted viscosity in both high and low viscous formulations, maintaining stability in high-salt environments while delivering superior sensorial properties through cold-processing compatibility.
With approximately 40% of new APIs hindered by poor water solubility, pharmaceutical companies face significant bioavailability challenges affecting efficacy, side effect profiles, and market competitiveness. Clariant addresses these challenges with our comprehensive range of PEGs and PEG-derivatives that effectively enhance API solubility. Our specialized solubilizers improve bioavailability and therapeutic performance while accelerating time-to-market for pharmaceutical formulations.
FDA approvals for sensitive pharmaceutical delivery systems have increased significantly as treatments for chronic and rare diseases expand. Clariant supports these formulations with premium excipients: VitiPure LEX (Low endotoxin excipients for sensitive formulations) and VitiPure Superior (Highly purified excipients for sensitive APIs into sensitive formulations).
