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Atención médica: excipientes
Solubilizadores para aplicaciones estándar

Aproximadamente el 40 % de las nuevas entidades químicas que se inventan como API relevantes para posibles enfermedades presentan dificultades para disolverse en el agua y no se absorben con facilidad en el tracto gastrointestinal debido a que sus estructuras químicas o perfiles de absorción son complejos, lo que conduce al fracaso. Esto aumenta la presión sobre las compañías farmacéuticas, no solo desde el punto de vista financiero, sino porque también pierden su ventaja competitiva y la velocidad de comercialización. La escasa biodisponibilidad de los API tiene como resultado no solo una eficacia reducida de los medicamentos, sino efectos secundarios indeseables tras su aplicación.

¿Cómo puede Clariant ayudarlo a obtener una solución? Ofrecemos una amplia gama de solubilizantes que aumentarán el rendimiento del API

  • PEG
  • Derivados del PEG

Los formuladores farmacéuticos pueden aumentar la biodisponibilidad del ingrediente farmacéutico activo (API) mediante el uso de excipientes para la mejora de la solubilidad, lo que también agiliza el lanzamiento de mercado.

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