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Solubilizers for Standard Applications

Health Care Excipients

With approximately 40% of new APIs hindered by poor water solubility, pharmaceutical companies face significant bioavailability challenges affecting efficacy, side effect profiles, and market competitiveness. Clariant addresses these challenges with our comprehensive range of PEGs and PEG-derivatives that effectively enhance API solubility. Our specialized solubilizers improve bioavailability and therapeutic performance while accelerating time-to-market for pharmaceutical formulations.

Related products

  • VitiPure HCO 40
    VitiPure HCO 40 is versatile non-ionic solubilizer and emulsifier enhancing the solubility and bioavailability of hydrophobic APIs and fat-soluble vitamins. VitiPure HCO 40 is obtained by reacting 40 moles of ethylene oxide with 1 mole of hydrogenated castor oil. At the room temperature it appears as white to yellowish paste. VitiPure HCO 40 is suitable for SEDDS and SMEDDS. It is typically used into formulations such as Topicals (Cream, Hot processing), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Soft shell capsules, Tablets, Instant & modified release), Liquid preparations (Solution).
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  • VitiPure CO 35
    VitiPure CO 35 is a non-ionic solubiliser and emulsifying agent for the human and veterinary pharmaceutical industries. It is made by reacting castor oil with ethylene oxide in a molar ratio of 1:35. At room temperature it appears as pale-yellow oily liquid. It forms clear solutions in water. It is typically used into formulations such as Topicals (Cream, Hot processing), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Soft shell capsules, Tablets, Instant release), Liquid preparations (Solution).
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  • VitiPure L 20
    VitiPure L 20 is a non-ionic, hydrophilic emulsifier, co-emulsifier and solubilizer. It is an oily, yellow or brownish-yellow, clear or slightly opalescent liquid with a faint odor. VitiPure L 20 can be used in various pharmaceutical formulations. It is typically used into formulations such as Topicals (Cold processing, Hot processing, Cream, Emulsion, Foam, Gel), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Soft shell capsules, Tablets, Instant release), Liquid preparations (Solution, Suspension) and Suppositories.
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  • VitiPure O 80
    VitiPure O 80 is a non-ionic, hydrophilic emulsifier, co-emulsifier, solubilizer and suspension stabilizer used widely in various biopharmaceutical formulations. It appears as amber liquid in room temperature with a faint characteristic odor. VitiPure O 80 has a broad working pH range and offers good skin tolerance. It is typically used into formulations such as Topicals (Cold processing, Hot processing, Cream, Emulsion, Foam, Gel, Hydrophilic ointment, Lipophilic ointment), Solid orals (Hot melt extrusion, Spray drying, Conventional pellets, Hard shell capsules, Multiple-unit tablets, Single-unit tablets, Soft shell capsules, Tablets, Enteric release, Instant release, Aqueous Coating), Liquid preparations (Solution, Suspension) and Suppositories.Generic name: Polysorbate 80
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  • VitiPure P 188 MG
    VitiPure P 188 MG is all rounder non-ionic polymer suitable for various pharmaceutical applications. It is supplied as a white to slightly yellowish flakes/powder with a waxy consistency. It is freely soluble in ethanol and water (opalescent solution). It is used as a wetting agent, emulsifier, solubilizer and bioavailability enhancer of poorly soluble APIs. It is typically used into formulations such as Topicals (Cream, Hot processing, Cold processing, Foam, Gel), Solid orals (Hot melt extrusion, Spray drying, Hard shell capsules, Instant release, extended release, matrix-type system, Reservoir-type system, Film), Liquid preparations (Solution). Generic name: Poloxamer 188 (Ph. Eur., USP/NF)
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